Research interests
Here are some of my research interests. Fully-funded research areas are pursued actively.
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Weakest peak from a CbCa(CO)NH experiment, for varying NUS sample sizes (M).
The use of non-uniform sampling (NUS) has long held the promise of collecting heteronuclear NMR spectra in record time. However, many are hesitant to implement relevant techniques in real-world experiments; the chief obstacle is predicting the smallest required sample that would be guaranteed to result in a high-quality spectrum.
By empirically determining minimal spectra for large numbers of high–resolution datasets, reliable guidelines for pre-determining an optimal NUS schedule can be recommended for each type of NMR experiment. Once empirical sampling rules for a sufficient number of experiments have been determined, we hope to establish a physical basis for determining a structure's optimal sampling schedule.
(Conservative versions of these guidelines are already being used for structure determination experiments. For more information, c.f. ANZMAG proceedings or contact me using the details below.)
